To Evaluation of Effectiveness of Chelatory Therapy in Patients with Talassemia

Authors

  • Zaynutdinova D.L Tashkent medical academy, Tashkent
  • Qudratova M.F Tashkent medical academy, Tashkent
  • Qo’ziyeva M.G Tashkent medical academy, Tashkent
  • Muhammadaminova D.R Tashkent medical academy, Tashkent
  • Axtamov A.J. Tashkent medical academy, Tashkent

Keywords:

anemia, hemoglobinopathy, thalassemia, hemosiderosis

Abstract

The term “thalassemia” refers to a group of autosomal-recessive blood diseases charaeterized by a decrease in the synthesis of one of two types of polypeptide chains of globin (α or β), that form a molecule of adult hemoglobin(HbA, α2β2). This leads to a decrease in the filling of erythrocytes with hemoglobin and anemia. In Uzbekistan, the birth rate with this disease is 10-15 per year. At present in the Republic of Uzbekistan, 184 patients with thalassemia are registered at the Research Institute of Hematology and Blood Transfuzion at the Dispensary.

References

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Betty Sisla. Management of laboratory hematology. /Pod ed. Practical medicine Vorobeva A. I., 2011. 88-96 p.

Makhmudova S. A. Novye podkhody k diagnostike i lecheniyu beta-thalassemia u detey // Dissertation 1996. 135s

Rumyantseva A.G., Tokareva Yu.N., Smetaninoy N.S. Hemoglobinopathies and thalassemic syndromes. /Pod ed. Practical medicine, 2015, 448p.

Suleymanova D.N., Mamatkulova D.F. Risk of peregruzki sign and chelation therapy and thalassemia patients. //Methodicheskoe posobie. 2017. -30s

Zaynutdinova D.L., Suleymanova D.N. Dynamics of ferritin indicators during chelator therapy in hemosiderosis // New day in medicine. 2018.3 (23). S 128-132

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Published

2022-10-30

Issue

Vol. 13 (2022): TJM

Section

Articles

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How to Cite

To Evaluation of Effectiveness of Chelatory Therapy in Patients with Talassemia. (2022). Texas Journal of Multidisciplinary Studies, 13, 145-151. https://mail.zienjournals.com/index.php/tjm/article/view/2630

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