Impaired Endothelial Dysfunction In Patients With Ankylosing Spondylitis After Covid-19
DOI:
https://doi.org/10.62480/tjms.2024.vol39.pp33-40Keywords:
Ankylosing Spondylitis, COVID-19, Endothelial DysfunctionAbstract
Currently, there is no doubt about the importance of the role of impaired endothelial functional state in the development of vascular pathology in a number of diseases, including rheumatic. With the advent and largescale spread of a new coronavirus infection (COVID-19), a high rate of patient’s hospitalizations with ankylosing spondyloarthritis (AS) and the development of extrapulmonary complications, such as myocardial injuries, kidney damage and vascular thromboembolism, were noted. The development of this phenomenon confirms the connection with pronounced endothelial dysfunction and its damage. This article presents the results of evaluation of endothelial dysfunction in AS patients undergoing COVID-19.
References
Münzel, T., Sinning, C., Post, F., Warnholtz, A., Schulz, E., Mu¨nzel, T., & Mu¨nzel, M. (2009).
Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction.
https://doi.org/10.1080/07853890701854702.
Sanchez-Piedra, C., Diaz-Torne, C., Manero, J., Pego-Reigosa, J. M., Rúa-Figueroa, Í., Gonzalez-Gay,
M. A., Gomez-Reino, J., & Alvaro-Gracia, J. M. (2020). Clinical features and outcomes of COVID-19 in patients with rheumatic diseases treated with biological and synthetic targeted therapies. Annals of the
Rheumatic Diseases, 79(7), 988–990. https://doi.org/10.1136/annrheumdis-2020-217948.
D’Antiga, L. (2020). Coronaviruses and Immunosuppressed Patients: The Facts During the Third
Epidemic. Liver Transplantation, 26(6), 832–834. https://doi.org/10.1002/lt.25756
Uhrin, Z., Kuzis, S., & Ward, M. M. (n.d.). Exercise and Changes in Health Status in Patients With
Ankylosing Spondylitis. Retrieved August 22, 2021, from https://jamanetwork.com/
Steyers, C. M., & Miller, F. J. (2014). Endothelial Dysfunction in Chronic Inflammatory Diseases. Int.
J. Mol. Sci, 15, 11324–11349. https://doi.org/10.3390/ijms150711324
Liew, J. W., Castillo, M., Zaccagnino, E., Katz, P., Haroon, N., & Gensler, L. S. (2020). Patientreported Disease Activity in an Axial Spondyloarthritis Cohort during the COVID-19 Pandemic. 2(9), 533–
https://doi.org/10.1002/acr2.11174
Roux, C. H., Brocq, O., Gerald, F., Pradier, C., & Bailly, L. (2020). Clinical impact of COVID-19 on
a French population of spondyloarthritis patients. In Clinical Rheumatology (Vol. 39, Issue 11, pp. 3185–
. Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/s10067-020-05413-
Vasina, L. V., Petrishchev, N. N., & Vlasov, T. D. (2017). Markers of endothelial dysfunction.
Regional Blood Circulation and Microcirculation, 16(1), 4–15. https://doi.org/10.24884/1682-6655-2017-16-
-4-15
Stolwijk C, Boonen A, van Tubergen A, Reveille JD. Epidemiology of spondyloarthritis. Rheum Dis
Clin North Am. 2012;38:441–76.
Ward M.M, Deodhar A, Gensler LS, Dubreuil M, Yu D, Khan MA, Caplan L. 2019 Update of the
American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and
Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic
Axial Spondyloarthritis. Arthritis Rheumatol. 2019 Oct;71(10):1599-1613. doi: 10.1002/art.41042. Epub
Aug 22. PMID: 31436036; PMCID: PMC6764882.
Ciurea A, Kissling S, Bürki K, Baraliakos X, de Hooge M, Hebeisen M, Papagiannoulis E, Exer P,
Bräm R, Nissen MJ, Möller B, Kyburz D, Andor M, Distler O, Scherer A, Micheroli R. Current differentiation
between radiographic and non-radiographic axial spondyloarthritis is of limited benefit for prediction of
important clinical outcomes: data from a large, prospective, observational cohort. RMD Open. 2022
Feb;8(1):e002067. doi: 10.1136/rmdopen-2021-002067. PMID: 35110365; PMCID: PMC8811599.
M.Rakhimova, Kh.Akhmedov, M.Tagaeva, S.Sadikova, F.Razakova, F. Khalmetova. Endothelin-1
biomarker features in patients with ankylosing spondylitis after COVID-19// Journal of positive school
psychology. Vol 6. #6, 2022 p 9369-9375.
Matveeva N.Y., Makarova E.V., Eskin N.A., Sokolova T.V. Consequences of COVID-19 for the
musculoskeletal and peripheral nervous systems. Diagnosis of complications (literature review) // N.N.
Priorov Journal of Traumatology and Orthopedics. - 2022. - Vol. 29. - N. 1. - P. 65-77.
doi: 10.17816/vto105957
Prasad M, Leon M, Lerman LO, Lerman A. Viral Endothelial Dysfunction: A Unifying Mechanism
for COVID-19. Mayo Clin Proc. 2021 Dec;96(12):3099-3108. doi: 10.1016/j.mayocp.2021.06.027. Epub
Aug 19. PMID: 34863398; PMCID: PMC8373818.
Shevchuk S, Pavliuk O. DISORDERS OF STRUCTURAL AND FUNCTIONAL STATE OF BONE
TISSUE IN MEN WITH ANKYLOSING SPONDYLITIS, THEIR RELATION TO DISEASE COURSE.
Wiad Lek. 2021;74(8):1856-1862. PMID: 34537733.
Mahmudiono T. et al. The effect of flaxseed oil consumtion on blood pressure among patients with
metabolic syndrome and related disorders: A systematic review and meta‐analysis of randomized clinical trials
//Phytotherapy Research. – 2022. – Т. 36. – №. 10. – С. 3766-3773.
Rakhimova, M. B., Akhmedov, K. S., & Turaev, Y. A. (2021). Endothelial dysfunction as a link in the
pathogenesis of ankylosing spondylitis against the background of a new coronavirus
infection. ACADEMICIA: An International Multidisciplinary Research Journal, 11(3), 2493-2498
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
User Rights
Under the Creative Commons Attribution-NonCommercial 4.0 International (CC-BY-NC), the author (s) and users are free to share (copy, distribute and transmit the contribution).
Rights of Authors
Authors retain the following rights:
1. Copyright and other proprietary rights relating to the article, such as patent rights,
2. the right to use the substance of the article in future works, including lectures and books,
3. the right to reproduce the article for own purposes, provided the copies are not offered for sale,
4. the right to self-archive the article.
