Phagocytic activity in people recovering from Corona Virus infection
Keywords:
Coronavirus, Phagocytosis, nitroblue tetrazolium, PolynuclearAbstract
The study aimed to measure the phagocytic activity of people recovering from Covid 19 after month and compare with people not infected as control. (100) samples of venous blood were collected randomly during the period from November 23, 2021 to March 23, 2022, and the result was 63 infections (40 male, 23 . female) and 37 not infected (20 male,17female). The number of people who recovered a month after infection was 63 (40 males and 23 females). The results of the study related to the phagocytic activity of cells were reached Polynuclear, with high significant differences at (P
<0.01 )in the optical absorbance rate, which reflects the extent of NBT staining reduction between persons recovering from Covid-19 virus and those without the disease.>
References
Nathan C. Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol. (2006) 6:173–82. doi: 10.1038/nri1785
Weiss SJ. Tissue destruction by neutrophils. N Engl J Med. (1989) 320:365– 76.
Tak T, Wijten P, Heeres M, Pickkers P, Scholten A, Heck AJ, et al. Human CD62Ldim neutrophils identified as a separate subset by proteome profiling and in vivo pulse-chase labeling. Blood (2017) 129:3476–85. doi: 10.1182/blood-2016-07-727669
Selders GS, Fetz AE, Radic MZ, Bowlin GL. An overview of the role of neutrophils in innate immunity, inflammation and host-biomaterial integration. Regenerat Biomater. (2017) 4:55–68. doi: 10.1093/rb/rbw041
Hellebrekers P, Vrisekoop N, Koenderman L. Neutrophil phenotypes in health and disease. Eur J Clin Invest. (2018) 23: e12943. doi: 10.1111/eci.12943
Leliefeld PH, Koenderman L, Pillay J. How neutrophils shape adaptive immune responses. Front Immunol. (2015) 6:471. doi: 10.3389/fimmu.2015.00471
Weber C, Noels H. Atherosclerosis: current pathogenesis and therapeutic options. Nat Med. (2011) 17:1410. doi: 10.1038/nm.2538
Soehnlein O. Multiple roles for neutrophils in atherosclerosis. Circul Res. (2012) 110:875–88. doi: 10.1161/CIRCRESAHA.111.257535
Hui DS, et al. The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health—the latest 2019 novel coronavirus outbreak in Wuhan, China. Inte J Infectious Dis. 2020;91:264–266. doi: 10.1016/j.ijid.2020.01.009. [PMC free article] [PubMed] [CrossRef]
Fong SJ, Li G, Dey N, Crespo RG, Herrera-Viedma E (2020) composite monte carlo decision making under high uncertainty of novel coronavirus epidemic using hybridized deep learning and fuzzy rule induction. arXiv preprint arXiv:2003.09868 [PMC free article] [PubMed]
"Symptoms of Coronavirus". U.S. Centers for Disease Control and Prevention (CDC). 13 May 2020. Archived from the original on 17 June 2020. Retrieved 18 June 2020.
Q&A on coronaviruses (COVID-19)". World Health Organization (WHO). 17 April 2020. Archived from the original on 14 May 2020. Retrieved 14 May 2020.
C. Rosales, “Neutrophils at the crossroads of innate and adaptive immunity,” Journal of Leukocyte Biology, vol. 108, no. 1, pp. 377–396, 2020.
F. D. Barr, C. Ochsenbauer, C. R. Wira, and M. Rodriguez-Garcia, “Neutrophil extracellular traps prevent HIV infection in the female genital tract,” Mucosal Immunology, vol. 11, no. 5, pp. 1420–1428, 2018.
Tahir N, et al. 2021 Sep 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 34033333
Tomar B, et al. Cells. 2020. PMID: 32498376
Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, et al. A neutrophil activation signature predicts critical illness and mortality in COVID-19. Blood Adv (2021) 5(5):1164–77.
Aschenbrenner AC, Mouktaroudi M, Krämer B, Oestreich M, Antonakos N, Nuesch-Germano M, et al. Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients. Genome Med (2021)
Granton E, Kim JH, Podstawka J, Yipp BG. The lung microvasculature is a functional immune niche. Trends Immunol (2018) 39:890–9.
Scapini P, Marini O, Tecchio C, Cassatella MA. Human neutrophils in the saga of cellular heterogeneity: insights and open questions. Immunol Rev (2016) 273:48–60.
Dinh HQ, Eggert T, Meyer MA, Zhu YP, Olingy CE, Llewellyn R, et al. Coexpression of CD71 and CD117 identifies an early unipotent neutrophil progenitor population in human bone marrow. Immunity (2020) 53:319–334.e6.
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